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ITGAM — TLR4

Text-mined interactions from Literome

Zhou et al., Am J Physiol Lung Cell Mol Physiol 2005 : Thus TLR4 signaling activates synthesis and upregulation of CD11b and is essential for PMN adhesion and transmigration ... Our data suggest an important role of TLR4 activated CD11b expression in the mechanism of the PMN host-defense response to LPS
Li et al., DNA Cell Biol 2009 : We found that TLR2 priming downregulates TLR4 transcription, and expression of TLR4 activation induced major histocompatibility complex II ( MHC II ), adhesion molecule intercellular adhesion molecule-1 ( ICAM-1 ), phagocytosis marker CD11b/CD18 , and Fcgamma receptor ( FcgammaR ) expression
Rostron et al., Transplantation 2010 (Body Weight...) : Desensitization of TLR4 also reduced ( P < 0.05 ) expression of the adhesive integrin CD11b on blood neutrophils after brain death
Elsenberg et al., PloS one 2013 (Atherosclerosis...) : We examined whether immediate TLR induced changes in CD11b and L-selectin ( CD62L ) expression are able to discriminate the presence and severity of atherosclerotic disease by exploring single dose whole blood TLR stimulation and detailed dose-response curves ... CAD patients showed a significantly higher L-selectin, but not CD11b response to TLR ligation than controls after single dose stimulations as well as significant differences in the hillslope and EC50 of the dose-response curves