Gene interactions and pathways from curated databases and text-mining

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IRF6 — TPO

Text-mined interactions from Literome

Zhang et al., J Interferon Cytokine Res 2010 (Inflammation) : LPS inhibited Tpo gene expression in astrocytes and microglia, but not in neurons, most likely due to absence of Toll-like receptor 4 in neurons ... In these cells, LPS significantly up-regulated Tpo mRNA expression
Nazar et al., Endocrinology 2012 : Moreover, LPS increased TSH stimulated TPO promoter activity ... Additionally, our results indicate that p65 phosphorylation of serine 536 constitutes an essential step in the p65 dependent , LPS induced transcriptional expression of TPO