Gene interactions and pathways from curated databases and text-mining

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IRF6 — SIRT1

Text-mined interactions from Literome

Lappas et al., Biol Reprod 2011 : SIRT1 expression, but not SIRT2, was down-regulated by lipopolysaccharide (LPS) and proinflammatory cytokines TNF and IL1B
Park et al., J Periodontal Res 2013 : Nicotine and LPS up-regulated the expression of SIRT1 mRNA and SIRT1 protein in a time- and concentration dependent manner