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CASP7 — IRF3
Text-mined interactions from Literome
Fantuzzi et al., Eur J Immunol 2001
:
In conclusion,
IRF-1 regulates IL-18 production and activity mostly by modulating expression of
caspase-1 and IL-18BP
Suk et al., J Pharmacol Exp Ther 2003
:
Moreover, baicalein inhibited LPS induced nuclear factor-kappaB (NF-kappaB) activity in BV-2 cells without affecting
caspase-11 activation,
interferon regulatory factor-1 induction , or signal transducer and activator of transcription-1 phosphorylation
Santic et al., Cell Microbiol 2010
(Tularemia) :
Initial sensing of F. tularensis in the cytosol triggers
IRF-3 dependent IFN-beta secretion, type I IFNR dependent signalling, activation of the inflammasome mediated by
caspase-1 , and a pro-inflammatory response, which is suppressed by triggering of SHIP
Moore et al., Virology 2011
:
B10S-IRF3 expression
augmented apoptotic
caspase activation and decreased viral RNA in TMEV infected macrophages while SJL-IRF3 increased viral replication with less caspase activation