Gene interactions and pathways from curated databases and text-mining

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IRAK1 — MAPK3

Text-mined interactions from Literome

Conner et al., J Exp Med 2009 : In the MOLF/Ei TLR signaling network, IRAK-2 promotes early nuclear factor kappaB (NF-kappaB) activity and is essential for the activation of p38 MAPK
Joh et al., Br J Pharmacol 2011 (Colitis...) : Kalopanaxsaponin A inhibited NF-?B and mitogen activated protein kinase activation induced by TNBS by suppressing IRAK-1 activation
Dauphinee et al., Am J Physiol Heart Circ Physiol 2011 : We find that Ga ( i/o ) -mediated activation of the MAPK is independent of the canonical MyD88, interleukin-1 receptor associated kinase , and tumor necrosis factor receptor associated factor 6 signaling cascade in LPS stimulated cells