Gene interactions and pathways from curated databases and text-mining

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INS — TLR4

Text-mined interactions from Literome

Pang et al., Diabetes 2010 (Hypoglycemia) : Further studies showed that TLR4 deficiency had no effect on insulin signaling and muscle proinflammatory cytokine production in response to fasting
Liu et al., Pulm Pharmacol Ther 2012 (Acute Lung Injury...) : Besides, insulin markedly inhibited the expression of toll-like receptor 2 (TLR2), toll-like receptor 4 (TLR4) and nuclear factor-?B ( NF-?B )
Betanzos-Cabrera et al., Nutr Hosp 2012 (Body Weight) : During obesity, the inflammatory pathway is triggered and insulin responsiveness is altered in fat tissue as a result of TLR4 activation by dietary lipids