Gene interactions and pathways from curated databases and text-mining

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IL6 — PPP2CA

Text-mined interactions from Literome

Boudreau et al., J Biol Chem 2002 : The PP2A inhibitor okadaic acid induced P. aeruginosa-like responses in mast cells including increased PKCalpha phosphorylation, stimulated PKC activity, and augmented IL-6 production, the last being blocked by the PKC inhibitor Ro 31-8220
Yokota et al., J Toxicol Sci 2008 (Pneumonia) : RPC also caused sustained elevations of granulocyte colony stimulating factor ( G-CSF ) and interleukin (IL)-6 levels in BALF
Nizamutdinova et al., J Cell Physiol 2013 (Hyperglycemia) : Moreover, ATRA and LGD1069 reversed the decreased PP2A activity and inhibited the activation of IKK/I?Ba and gene expression of MCP-1, IL-6 , and TNF-a in the hearts of Zucker diabetic fatty rats
Choi et al., Immunol Lett 1998 : In addition, co-transfection of protein phosphatase 2A (PP2A) antisense constructs further increased IL-6 induced IRF-1 promoter activity, suggesting that PP2A is involved in IL-6 signaling ... In addition, IL-6 directly induced the PP2A phosphorylation ... Furthermore, IL-6 activated PP2A activity simultaneously