Gene interactions and pathways from curated databases and text-mining

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IL6 — NOS1

Text-mined interactions from Literome

Galley et al., Crit Care Med 1999 (Shock, Septic) : To determine the effect of the nitric oxide synthase inhibitor, L-N ( G ) -monomethylarginine, on interleukin-6 and interleukin-8 accumulation, and nuclear factor-kappaB expression in an endothelial cell model of sepsis
Er et al., J Cataract Refract Surg 1999 : These findings suggest a strong inhibitory effect of NOS inhibitors and corticosteroids on aqueous levels of TNF-alpha and NO and no inhibitory effect on IL-1 beta and IL-6 levels after cataract surgery
Heitmeier et al., J Biol Chem 1999 (Insulinoma) : Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1 induced inducible nitric-oxide synthase expression by islets of Langerhans
Yu et al., J Biol Chem 2003 : JAK2/STAT3, not ERK1/2, mediates interleukin-6 induced activation of inducible nitric-oxide synthase and decrease in contractility of adult ventricular myocytes
Miljkovic et al., Cell Mol Life Sci 2003 : The role of interleukin-17 in inducible nitric oxide synthase mediated nitric oxide production in endothelial cells
Cattaruzza et al., J Biol Chem 2003 : Interleukin-10 induction of nitric-oxide synthase expression attenuates CD40 mediated interleukin-12 synthesis in human endothelial cells
Miljkovic et al., Cytokine Growth Factor Rev 2004 (Inflammation...) : Inducible nitric oxide synthase activation by interleukin-17
Ortega-Gutiérrez et al., FASEB J 2005 (Multiple Sclerosis) : Additionally, in microglial cells, UCM707 decreases the production of the proinflammatory cytokines tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6 ; reduces nitric oxide levels and inducible nitric oxide synthase expression ; and is able to potentiate the action of a subeffective dose of the endocannabinoid anandamide
Saura et al., J Biol Chem 2006 : Stat3 mediates interleukin-6 [ correction of interelukin-6 ] inhibition of human endothelial nitric-oxide synthase expression
Hung et al., J Hypertens 2010 (Atherosclerosis) : Interleukin-6 inhibits endothelial nitric oxide synthase activation and increases endothelial nitric oxide synthase binding to stabilized caveolin-1 in human vascular endothelial cells
Wang et al., Toxicological sciences : an official journal of the Society of Toxicology 2013 (Cystitis...) : Involvement of interleukin-6 regulated nitric oxide synthase in hemorrhagic cystitis and impaired bladder contractions in young rats induced by acrolein, a urinary metabolite of cyclophosphamide
Ning et al., PloS one 2013 (Inflammation...) : In addition, NaHS treatment prevented the increase of nitric oxide, Intercellular Adhesion Molecule 1 ( ICAM-1 ) and interleukin (IL)-6 production and inducible nitric oxide synthase activation induced by TNF-a
Szabó et al., Eur J Pharmacol 1993 : We investigated the role of interleukin-1 in the induction of a Ca ( 2+ ) -independent nitric oxide ( NO ) synthase by bacterial endotoxin in vivo
Tetsuka et al., Proc Natl Acad Sci U S A 1994 : Cross-talk between cyclooxygenase and nitric oxide pathways : prostaglandin E2 negatively modulates induction of nitric oxide synthase by interleukin 1
Kanno et al., Hypertension 1993 : Induction of nitric oxide synthase gene by interleukin in vascular smooth muscle cells
Duval et al., Mol Pharmacol 1996 : Induction of hepatic nitric oxide synthase (NOS) by tumor necrosis factor-alpha (TNF alpha), interleukin-1 beta (IL-1 beta), interferon-gamma (IFN gamma), interleukin-6 (IL-6) , and lipopolysaccharide was assessed as activity and immunoreactive protein
Heitmeier et al., J Biol Chem 1997 : Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1
Hauber et al., Cell Immunol 1997 : We show that gene expression of IL-1 alpha, IL-1 beta, IL-6 , granulocyte-colony stimulating factor, and IL-10 was induced in both cell fractions, whereas increased mRNA levels of interferon-gamma and the inducible nitric oxide synthase were exclusively detected in the patients ' nonadherent MNCs