Gene interactions and pathways from curated databases and text-mining

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IGF1 — IL4

Text-mined interactions from Literome

Yam et al., J Biol Chem 2001 (MAP Kinase Signaling System) : Characterization of insulin-like growth factor I (IGF-I) receptor mutants for their effects on IGF-I- and interleukin 4-mediated DNA synthesis of 32D cells
Kim et al., Mol Cells 2003 : IGF-1 increased the activity of signal transducer and activator of transcription 6 ( STAT6 ) in response to IL-4 , and activated NF-(kappa)B
Wynes et al., J Leukoc Biol 2004 (Pulmonary Fibrosis) : IL-4 induced macrophage derived IGF-I protects myofibroblasts from apoptosis following growth factor withdrawal
Méndez-Dávila et al., J Endocrinol Invest 2004 (Osteoporosis) : We investigated the effects of 17betaestradiol and two selective estrogen receptor modulators, tamoxifen and raloxifene, on the expression and release of constitutive and interleukin-1 stimulated interleukin (IL)-6, transforming growth factor-beta1 ( TGF-beta1 ) and insulin-like growth factor-1 by osteoblasts in primary culture from trabecular bone of healthy post-menopausal women
Glazebrook et al., J Vasc Res 1998 : Regulation of insulin-like growth factor-1 expression in vascular endothelial cells by the inflammatory cytokine interleukin-1