Gene interactions and pathways from curated databases and text-mining

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IL31 — STAT3

Text-mined interactions from Literome

O'Brien et al., J Biol Chem 1999 : STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130 utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroid hormone
Dambacher et al., Gut 2007 (Cytomegalovirus Infections...) : IL31 mediates ERK-1/2, Akt, STAT1, and STAT3 activation in IEC resulting in enhanced IEC migration
Ozawa et al., Journal of ophthalmology 2011 : In innate chorioretinal inflammation, interleukin-6 family ligands induce STAT3 activation in photoreceptors, which causes UPS mediated excessive degradation of the visual substance, rhodopsin
Lee et al., Br J Dermatol 2012 (Dermatitis, Atopic) : IL-31 receptor activation resulted in calcium influx and STAT3 activation ; pretreatment with STAT3 inhibitor stopped the increase of ß-endorphin
Kasraie et al., Allergy 2013 : Interleukin-31 strongly activated STAT-1 and 5 but not STAT-3 in human macrophages after up-regulation of IL-31 receptor with staphylococcal exotoxins