Gene interactions and pathways from curated databases and text-mining

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IL12A — IL3

Text-mined interactions from Literome

La Flamme et al., PloS one 2012 : Instead, we found that derivation culture conditions ( GM-CSF plus IL-3 versus M-CSF ) could explain the different responses of BALB/c and IL-4Ra-/- macrophages, and these cytokines shaped the ensuing macrophage such that GM-CSF plus IL-3 promoted more IL-12 and IL-4 while M-CSF led to higher IL-10 production
Ploemacher et al., Leukemia 1993 : In IL-3 + SF-containing cultures, IL-12 further increased colony numbers and a higher percentage of colonies expressed neutrophilic, megakaryocytic, erythroid, monocytic, blast cell, and/or mast cell lineages
Ploemacher et al., Leukemia 1993 : Previous data have shown that IL-12 may act as a potent synergistic factor stimulating multilineage expression of hemopoietic stem cells in the presence of IL-3 in combination with Steel factor ( SF ) or IL-11
Hegde et al., Cell Immunol 1995 (Neoplasms, Experimental) : AK-5 tumor induced expression of interleukin-12 : role of IL-12 in NK-mediated AK-5 regression
Quelle et al., Mol Cell Biol 1995 : In contrast, IL-2, IL-3 , and erythropoietin induce the tyrosine phosphorylation of Stat5 while IL-12 uniquely induces the tyrosine phosphorylation of Stat4
Morris et al., J Immunol 1994 : In untreated mice IL-12 enhanced IFN-gamma and IL-10 gene expression and protein secretion, reduced base line IL-3 and IL-4 gene expression, and increased serum IgG2a concentration
Finkelman et al., J Exp Med 1994 (Intestinal Diseases, Parasitic...) : IL-12 stimulated IFN-gamma and IL-10 gene expression during primary and secondary N. brasiliensis infections and inhibited IL-3 , IL-4, IL-5, and IL-9 gene expression during primary infections but had little inhibitory effect during secondary infections