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IL25 — IL5
Text-mined interactions from Literome
Suchin et al., J Am Acad Dermatol 2001
(Eosinophilia...) :
Increased
interleukin 5 production in eosinophilic Sézary syndrome :
regulation by interferon alfa and
interleukin 12
Fort et al., Immunity 2001
(Eosinophilia...) :
IL-25 induces IL-4,
IL-5 , and IL-13 and Th2 associated pathologies in vivo
Maezawa et al., J Immunol 2006
(MAP Kinase Signaling System) :
IL-25 ( IL-17E )
induces IL-4,
IL-5 , and IL-13 production from an unidentified non-T/non-B cell population and subsequently induces Th2-type immune responses such as IgE production and eosinophilic airway inflammation
Tamachi et al., Int Arch Allergy Immunol 2006
(Asthma...) :
Interestingly, when systemically administered to mice,
IL-25 induces IL-4,
IL-5 and IL-13 production from undefined non-T/non-B cells and then induces Th2-type immune responses such as blood eosinophilia and increased serum immunoglobulin E levels
Rickel et al., J Immunol 2008
:
Unlike wild-type mice, cultured splenocytes from either IL-17RB KO or IL-17RA KO mice did not produce
IL-5 or IL-13 in
response to
IL-25 stimulation, and both IL-17RB KO and IL-17RA KO mice did not respond to intranasal administration of IL-25
Swaidani et al., J Immunol 2009
(Eosinophilia...) :
Although Act1-deficient mice showed reduced expression of KC ( CXCL1 ) and neutrophil recruitment to the airway compared with wild-type mice in response to IL-17 stimulation, Act1 deficiency abolished
IL-25 induced expression of IL-4,
IL-5 , IL-13, eotaxin-1 ( CCL11 ), and pulmonary eosinophilia
Ikutani et al., J Immunol 2012
(Lung Neoplasms...) :
Innate non-T IL-5 producing cells localized most abundantly in the lung and proliferated and upregulated
IL-5 production in
response to
IL-25 and IL-33
Yang et al., PloS one 2013
:
Macrophages produced type 2 cytokines
IL-5 and IL-13 in
response to the stimulation of
IL-25/IL-33 in vitro, or were the IL-13 producing cells in mice administrated with exogenous IL-33 or infected with Heligmosomoides bakeri
Licona-Limón et al., Nat Immunol 2013
(Hypersensitivity) :
Such studies have led to the identification of a new innate lymphoid subset that produces the canonical type 2 cytokines
IL-5 , IL-9 and IL-13 in
response to
IL-25 and IL-33
Swain et al., Proc Natl Acad Sci U S A 1981
:
We conclude that the C.C3.11.75
TRF activity is not
due to
interleukin 1 or to interleukin 2 but to a third factor provisionally designated as ( DL ) TRF
Zaitseva et al., Infect Immun 1995
:
Gamma interferon ( IFN-gamma ),
interleukin-2 (IL-2), IL-4, and
IL-5 induction was assayed by mRNA-specific PCR and by enzyme linked immunosorbent assay and bioassay for protein production