Gene interactions and pathways from curated databases and text-mining

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IL2 — NOS1

Text-mined interactions from Literome

Heitmeier et al., J Biol Chem 1999 (Insulinoma) : Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1 induced inducible nitric-oxide synthase expression by islets of Langerhans
Jyothi et al., Scand J Immunol 2000 (Neoplasms, Experimental) : Interleukin-2 induced nitric oxide synthase and nuclear factor-kappaB activity in activated natural killer cells and the production of interferon-gamma
Erickson et al., Urology 2001 (Cystitis, Interstitial) : Markers that changed after treatment were as follows : ( 1 ) nitric oxide synthase and cyclic guanosine monophosphate increased with oral L-arginine ; ( 2 ) ECP decreased with subcutaneous heparin ; ( 3 ) prostaglandin E ( 2 ) and kallikrein decreased after bladder distention ; ( 4 ) neutrophil chemotactic activity decreased after dimethyl sulfoxide ; ( 5 ) IL-2 inhibitor decreased after oral nifedipine ; ( 6 ) IL-2, IL-6, and IL-8 decreased after bacille Calmette-Guérin ( BCG ) vaccine ; and ( 7 ) APF and heparin binding epidermal growth factor changed to or toward normal levels after bladder distention or sacral nerve stimulation
Miljkovic et al., Cell Mol Life Sci 2003 : The role of interleukin-17 in inducible nitric oxide synthase mediated nitric oxide production in endothelial cells
Cattaruzza et al., J Biol Chem 2003 : Interleukin-10 induction of nitric-oxide synthase expression attenuates CD40 mediated interleukin-12 synthesis in human endothelial cells
Miljkovic et al., Cytokine Growth Factor Rev 2004 (Inflammation...) : Inducible nitric oxide synthase activation by interleukin-17
Qian et al., Vascul Pharmacol 2006 (Diabetes Mellitus, Experimental) : IL-2 ( 1000 U/ml ) significantly attenuated the decrease of SOD and NOS activity caused by high glucose
Szabó et al., Eur J Pharmacol 1993 : We investigated the role of interleukin-1 in the induction of a Ca ( 2+ ) -independent nitric oxide ( NO ) synthase by bacterial endotoxin in vivo
Tetsuka et al., Proc Natl Acad Sci U S A 1994 : Cross-talk between cyclooxygenase and nitric oxide pathways : prostaglandin E2 negatively modulates induction of nitric oxide synthase by interleukin 1
Kanno et al., Hypertension 1993 : Induction of nitric oxide synthase gene by interleukin in vascular smooth muscle cells
Karanth et al., Proc Natl Acad Sci U S A 1993 : The data indicate that IL-2 can activate constitutive NOS leading to increased NO release, which activates CRF release
Leder et al., Eur Surg Res 1996 (Lung Neoplasms...) : To elucidate whether inhibition of the IL-2 induced NOS could boost efficacy of IL-2 stimulated CTLs in vivo, we assessed lung metastases in mice injected with IL-2, the NOS inhibitor aminoguanidine ( AG ), their combination and the diluent
Heitmeier et al., J Biol Chem 1997 : Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1
Williams et al., J Immunol 1998 : TCR stimulated expression of functional Fas ligand was attenuated in a stereospecific manner by NOS inhibitors, but these compounds did not inhibit TCR stimulated IL-2 secretion or CD69 surface expression