Gene interactions and pathways from curated databases and text-mining

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CASP7 — IL1RN

Text-mined interactions from Literome

Maedler et al., Proc Natl Acad Sci U S A 2004 (Diabetes Mellitus, Type 2) : Antagonizing IL-1Ra by introduction of small interfering RNA to IL-1Ra into human islets led to caspase-3 activation, DNA fragmentation, and impaired beta cell function
Maron-Gutierrez et al., Eur Respir J 2011 (Pulmonary Fibrosis...) : Nevertheless, caspase-3 , IL-1ß, IL-1a, IL-1RN and TGF-ß mRNA expression diminished after cell therapy