Gene interactions and pathways from curated databases and text-mining

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IGF2 — IL1B

Text-mined interactions from Literome

Anwar et al., Circulation 2002 (Arteriosclerosis) : IL-1beta , IL-6, and IFN-gamma did not regulate IGF-1, IGF-1 receptor (R), or IGF binding proteins ( IGFBPs )
Ueland et al., J Clin Endocrinol Metab 2010 (Acromegaly...) : In macrophages, IGF-I/GH significantly decreased the release of IL-1Ra and increased IL-1beta , suggesting that the decreased circulating IL-1Ra levels in acromegaly could reflect both direct and indirect mechanisms