Gene interactions and pathways from curated databases and text-mining

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IL1A — IL22

Text-mined interactions from Literome

De Caterina et al., Am J Clin Nutr 2000 (Arteriosclerosis) : Consumption of the n-3 fatty acid docosahexaenoic acid ( DHA ; 22 : 6n-3 ) reduced endothelial expression of vascular cell adhesion molecule 1 ( VCAM-1 ), E-selectin, intercellular adhesion molecule 1 ( ICAM-1 ), interleukin 6 (IL-6), and IL-8 in response to IL-1 , IL-4, tumor necrosis factor, or bacterial endotoxin, with a half-maximal inhibitory concentration ( IC ( 50 ) ) of 1-25 micromol, ie, in the range of nutritionally achievable plasma concentrations
Zeyse et al., Biol Reprod 2000 : Induction of interleukin-1alpha production in murine Sertoli cells by interleukin-1
Van Damme et al., J Invest Dermatol 1990 : This study focuses on interferon-beta (IFN-beta), interleukin-6 (IL-6), and interleukin-8 (IL-8) production by fibroblasts and epithelial cells in response to interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha)
Elias et al., Chest 1990 (Pneumonia...) : To understand the processes regulating inflammation and fibrosis in the human lung, we characterized the effects of recombinant interleukin-1 , tumor necrosis factor, and gamma interferon on fibroblast proliferation, collagen production, interleukin-1-alpha production, interleukin-1-beta production, and interleukin-6 production
Ness-Schwickerath et al., Cell Mol Life Sci 2011 : In contrast, IL-17A and IL-22 production by murine ?d T cells is innately programmed during thymic ontogeny but requires IL-23 and IL-1ß for maintenance
Wang et al., PloS one 2011 (Liposarcoma) : IL-22 overexpression promotes production of inflammatory cytokines such as IL-1ß and IL-10 and stimulates ERK phosphorylation in adipose tissue ... Furthermore, IL-22 treatment in differentiated 3T3-L1 adipocytes could induce IL-1ß and IL-10 expression, together with stimulation of ERK phosphorylation
Seckinger et al., J Immunol 1987 (Fever) : A urine inhibitor of interleukin 1 activity affects both interleukin 1 alpha and 1 beta but not tumor necrosis factor alpha
Grosset et al., Blood 1995 : In vitro biosynthesis of leukemia inhibitory factor/human interleukin for DA cells by human endothelial cells : differential regulation by interleukin-1 alpha and glucocorticoids
Boxman et al., J Invest Dermatol 1993 : Low interleukin-1 activity was most probably not due to inhibition of interleukin-1 alpha production in squamous carcinoma cells-4/3T3 co-cultures because interleukin-1 alpha messenger RNA expression in squamous carcinoma cells-4 cells remained unchanged in the presence of 3T3 cells