Gene interactions and pathways from curated databases and text-mining

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IL12A — IL1A

Text-mined interactions from Literome

Chieppa et al., J Immunol 2003 (Inflammation) : MUC III ( a partially purified mucin ), biglycan ( a purified complex proteoglycan ), and mannosylated lipoarabinomannan from Mycobacterium tuberculosis affected cytokine production with high IL-10, IL-1R antagonist, IL-1R type II, and inhibition of IL-12
Mpiga et al., Scand J Immunol 2006 (Chlamydia Infections) : When infected HeLa cells were co-cultured with THP-1 cells, IL-6 and IL-8 secretion was sustained, IL-1beta expression followed a bell shaped curve and IL-10, IL-12p70 and TNF-alpha synthesis was down regulated
Cheng et al., Int Immunopharmacol 2008 : The production of IL-1 was induced by GP at a dose of 10 microg/mL ; but, NO, IL-6 and IL-12 was significantly induced at 100 microg/mL
Enríquez-de-Salamanca et al., Cytokine 2008 (Conjunctivitis, Allergic...) : TNF-alpha stimulated secretion of IL-12p40 was significantly increased by 30 min ; GM-CSF, MCP-1, IL-6, IL-7, IL-8, and RANTES were significantly increased by 2 h, and IFN-gamma and IL-1alpha by 24 h
Tomizawa et al., Rheumatology (Oxford) 2010 (Glomerulonephritis...) : In contrast, the IL-1alpha level increased, and IL-17 and IL-12p70 slightly increased with DSG treatment
Donini et al., Prostate 2012 (Prostatic Neoplasms) : LNCaP enhance IL-1ß , IL-23, IL-6, and TNF-a secretion by decreasing glucan dependent NADPH oxidase activity, whereas glucan increases IL-12 production through NADPH oxidase unrelated mechanisms
Mutamba et al., Eur J Immunol 2012 : Furthermore, IL-1F8 stimulated increased CD40 and CD80 expression and IL-18 and IL-12 p70 production by MDDCs, which induced proliferation of IFN-? producing CD3 ( + ) lymphocytes ( indicative of inflammatory Th1 subsets )
Kim et al., J Immunol 2012 (Disease Models, Animal...) : PLC activation enhanced the bactericidal activity and hydrogen peroxide production of mouse neutrophils, and it also enhanced the production of IFN-? and IL-12 while inhibiting proseptic TNF-a and IL-1ß production in cecal ligation and puncture mice
Burnham et al., Am J Physiol Lung Cell Mol Physiol 2013 (Alcoholism) : Cigarette smoking duration was associated with higher IL-1ß ( P = 0.0009 ) but lower VEGF ( P = 0.0007 ) ; cigarette smoking intensity was characterized by higher IL-1ß and lower VEGF and diminished IL-12 ( P = 0.0004 )
Grewe et al., J Immunol 1998 : The expression of both IL-12 protein and mRNAs for the p35 and p40 IL-12 subunits was strongly induced in all donors by the Th2-like cytokines IL-4 and granulocyte-macrophage CSF and was also moderately induced by TNF-alpha and IL-1alpha