Gene interactions and pathways from curated databases and text-mining

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IGF2 — IL1A

Text-mined interactions from Literome

Nawrat et al., Pharmacol Res 2005 : Instead, IL-1 was found to inhibit the expression of insulin-like growth factor-I receptor ( IGF-IR ) and MAP kinases-ERK1 and ERK2, while HA was shown to counteract this process
Hill et al., Peptides 1988 : In preliminary studies excess IGF-II was shown to inhibit the binding of radiolabeled IGF-II and IL-1 but not anti-Thy 1.1 ... Similarly, IL-1 inhibited the binding of radiolabeled IL-1 and IGF-II but not anti-Thy 1.1 ... Anti-Thy 1.1 inhibited the binding of IGF-II and IL-1, but was not inhibited by either IGF-II or IL-1
Lang et al., Am J Physiol 1996 (Bacteremia...) : The purpose of the present investigation was to determine whether endogenously produced interleukin (IL)-1 mediates the changes in insulin-like growth factor (IGF) I and IGF binding proteins ( IGFBP ) induced by chronic abdominal sepsis in rats and to correlate the changes in the IGF system with the alternations in protein synthesis