Gene interactions and pathways from curated databases and text-mining

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CREB1 — IL1A

Text-mined interactions from Literome

Song et al., Mucosal Immunol 2012 (Metaplasia...) : Stimulation with IL-1ß caused the direct binding of NF-?B and CREB to the MUC5AC promoter, thus increasing MUC5AC gene expression
Galardo et al., J Endocrinol Invest 2013 : The aim of this study was to investigate if bFGF and IL1ß activate CREB , what signaling pathways may be participating and the possible relationship between CREB activation and the regulation of Sertoli cell function ... The results presented herein suggest that CREB is stimulated in response to bFGF and IL1ß through p42/p44-MAPK and p38-MAPK pathways and that this transcription factor may be partially responsible for the regulation of Sertoli cell function
Tong et al., J Neurosci 2012 : Using rat organotypic hippocampal cultures, we found that IL-1ß suppressed BDNF dependent regulation of Arc and phosphorylation of cofilin and cAMP response element binding protein ( CREB ), a transcription factor regulating Arc expression