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IKBKB — TLR4

Pathways - manually collected, often from reviews:

• Reactome Reaction: IKBKB → TLR4 (indirect_complex) Wu et al., Nat Cell Biol 2006, Ea et al., Mol Cell 2006
• Reactome Reaction: IKBKB → TLR4 (reaction) Wu et al., Nat Cell Biol 2006, Ea et al., Mol Cell 2006

Text-mined interactions from Literome

Medina-Tamayo et al., Inflamm Res 2011 : No change in TLR4 , CD14 or MD-2 expression was detected after the IgE dependent sensitization process, whereas TLR4 dependent phosphorylation of IKK and I?B was augmented
Kim et al., Gastroenterology research and practice 2010 : TLR4 , expressed in insulin target tissues, activates proinflammatory kinases JNK, IKK , and p38 that impair insulin signal transduction directly through inhibitory phosphorylation of insulin receptor substrate (IRS) on serine residues
Avila et al., Innate Immun 2012 : Lyn kinase controls TLR4 dependent IKK and MAPK activation modulating the activity of TRAF-6/TAK-1 protein complex in mast cells
Tong et al., Cell Res 2012 : NLRC5 ablation reduces MHC class I expression, and enhances IKK and IRF3 phosphorylation in response to TLR stimulation or viral infection