Gene interactions and pathways from curated databases and text-mining

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CASP5 — IGFBP3

Text-mined interactions from Literome

Kim et al., Cancer Res 2004 (Breast Neoplasms) : Induction of IGFBP-3 using an ecdysone-inducible expression system inhibited DNA synthesis in an IGF-IGF receptor axis independent fashion and resulted in the subsequent induction of apoptosis and an increase in caspase activity
Dar et al., J Invest Dermatol 2010 (Melanoma...) : IGFBP3 overexpression also resulted in cleavage of caspase 3 and reduced expression of phosphorylated AKT