Gene interactions and pathways from curated databases and text-mining

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AKT1 — IFNGR2

Text-mined interactions from Literome

Martin et al., Endocrinology 2000 : Studies using mutants of ER-alpha demonstrated that Akt increased estrogen receptor activity through the amino-terminal activation function-1 (AF-1)
Campbell et al., J Biol Chem 2001 (Breast Neoplasms) : Although PI 3-kinase increased the activity of both estrogen independent activation function 1 (AF-1) and estrogen dependent activation function 2 ( AF-2 ) of ERalpha, AKT increased the activity of only AF-1