Gene interactions and pathways from curated databases and text-mining

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IFNG — IGF2

Text-mined interactions from Literome

Shalita-Chesner et al., Mol Cell Endocrinol 2001 : This effect was associated with significant reductions in the levels of IGF-l-R mRNA and protein, and with inhibition of IGF-l-R promoter activity, suggesting that TNF-alpha and IFN-gamma affect IGF-l-R gene expression at the transcriptional level
Anwar et al., Circulation 2002 (Arteriosclerosis) : IL-1beta, IL-6, and IFN-gamma did not regulate IGF-1, IGF-1 receptor (R), or IGF binding proteins ( IGFBPs )
Shalita-Chesner et al., J Pediatr Endocrinol 2004 (Bone Neoplasms...) : The potential involvement of STAT proteins in transcriptional regulation of the IGF-IR gene by IFN-gamma was addressed by transient coexpression of vectors encoding STAT1 and STAT5b, together with an IGF-IR promoter luciferase reporter, in the osteosarcoma derived cell line Saos-2
Jia et al., Am J Physiol Heart Circ Physiol 2007 (Carotid Artery Diseases...) : Here we assessed the expression of IGF-I receptor (IGF-IR) in atherosclerotic plaques and in plaque VSMCs of asymptomatic and symptomatic patients with carotid stenosis and examined the effect of IGF-I, IL-12, and IFN-gamma on the expression of IGF-IR and IGF binding protein (IGFBP)-3 in plaque VSMCs
Hu et al., Mol Hum Reprod 2008 : IFN-gamma relatively increased IGF-1 and -2 secretion
Ilvesmäki et al., Mol Cell Endocrinol 1993 : Tumor necrosis factor-alpha and interferon-gamma inhibit insulin-like growth factor II gene expression in human fetal adrenal cell cultures
Martin et al., J Neurosci Res 1993 (Brain Neoplasms...) : Interferon-gamma inhibits DNA synthesis and insulin-like growth factor-II expression in human neuroblastoma cells ... In this study, we determined the effects of IFN-gamma on cellular growth and expression of insulin-like growth factor II (IGF-II) and IGF receptors in the human neuroblastoma cell line SH-SY5Y