Gene interactions and pathways from curated databases and text-mining

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CXCR4 — IFI44

Text-mined interactions from Literome

Chernock et al., Blood 2001 : We and others have shown that the binding of SDF-1alpha to CXCR4 activates phosphatidylinositol-3 kinase ( PI-3 kinase ), p44/42 mitogen associated protein kinase, and the transcription factor nuclear factor-kappaB, and it also enhances the tyrosine phosphorylation and association of proteins involved in the formation of focal adhesions
Scotton et al., Cancer Res 2002 (Neoplasm Invasiveness...) : Ligand stimulation of the CXCR4 receptor resulted in sustained activation of Akt/protein kinase B and biphasic phosphorylation of p44/42 mitogen activated protein kinase in IGROV