Correale et al., Ann Neurol 2010
(Multiple Sclerosis) :
CD8+ CD25+ FoxP3+ cells downregulated costimulatory molecule expression on dendritic cells through a STAT3 mediated pathway, resulting in less efficient antigen presentation, and induced IDO expression on DCs through STAT3 and cytotoxic T-lymphocyte antigen 4-dependent mechanisms
Sumpter et al., J Immunol 2012
:
Hepatic stellate cells undermine the allostimulatory function of liver myeloid dendritic cells via STAT3 dependent induction of IDO Yu et al., J Immunol 2013
(Breast Neoplasms...) :
Together, our findings suggest that STAT3 dependent IDO expression mediates immunosuppressive effects of MDSCs in breast cancer
Reddy et al., Trans Am Clin Climatol Assoc 2013
:
HDACis reduce DC responses by enhancing the expression of indoleamine 2,3 dioxygenase (IDO) in a STAT-3 dependent manner