Gene interactions and pathways from curated databases and text-mining

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IDO1 — NOS1

Text-mined interactions from Literome

Däubener et al., Adv Exp Med Biol 1999 : We were able to show that the IL-1 and TNF-alpha mediated inhibition of IFN-gamma induced IDO activity in uroepithelial cells is due to stimulation of inducible nitric oxide synthase
Franchi et al., Nitric Oxide 2001 : This study was conducted to investigate the in vitro and in vivo effects of lysine clonixinate ( LC ) and indomethacin (INDO) on NOS activity in rat lung preparation
Jackman et al., Naunyn Schmiedebergs Arch Pharmacol 2011 (Disease Models, Animal...) : Mice were pre treated with vehicle, the Ido1 inhibitor, 1-methyl-D-tryptophan ( 1-MT ; 50 mg/kg i.p. ) or the inducible nitric oxide synthase ( Nos2 ) inhibitor , aminoguanidine ( AG, 100 mg/kg i.p. )
Darcy et al., PloS one 2011 (Sepsis) : Increased IDO activity ( measured by the kynurenine to tryptophan [ KT ] ratio in plasma ) causes T-cell apoptosis, vasodilation and nitric oxide synthase inhibition
Alberati-Giani et al., J Immunol 1997 : In MT2 macrophages, the induction of IDO activity by IFN-gamma was further increased by the presence of NOS inhibitors, whereas culturing of IFN-gamma activated MT2 cells with NO generators produced a marked reduction of IDO activity expression