Gene interactions and pathways from curated databases and text-mining

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ID2 — IGF2

Text-mined interactions from Literome

Belletti et al., J Biol Chem 2001 : Specifically, we found that the IGF-IR activated by its ligand was a strong inducer of Id2 gene expression in 32D murine hemopoietic cells ... The role of PI3K activity in the up-regulation of Id2 gene expression by the IGF-IR was confirmed by different methods and in different cell types
Prisco et al., Mol Cell Biol 2001 : These results indicate that in 32D cells, the IGF-IR regulates the expression of the Id2 gene and that this regulation is modulated by both positive and negative signals
Wahdan-Alaswad et al., Cancer Res 2010 (Prostatic Neoplasms) : Similarly, IGF-I suppressed BMP4 induced transcription of the Id1, Id2 , and Id3 genes that are crucially involved in prostate tumor progression through PI3K dependent and mTORC1/2 dependent mechanisms