Gene interactions and pathways from curated databases and text-mining

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ICAM1 — PARP14

Text-mined interactions from Literome

Sharp et al., Inflammation 2001 (Inflammation) : Enzyme linked immunosorbent analysis ( ELISA ) was used to assess if ICAM-1 , VCAM-1, and E-selectin were expressed at the cell surface, and if PARP inhibition ( using the selective PARP inhibitor GPI 6150 ) blocked the induced expression ... PARP inhibition with GPI 6150 blocked the IL-1beta mediated stimulation of both ICAM-1 and E-selectin expression, and blocked TNF-alpha stimulation of ICAM-1 expression at 24 h
Cuzzocrea et al., Biochem Pharmacol 2002 (Disease Models, Animal...) : The potent PARP inhibitor 5-aminoisoquinolinone ( 5-AIQ ) reduced the degree of lung injury and attenuated the expression of P-selectin and ICAM-1 as well as the recruitment of neutrophils into the injured lung
Cuzzocrea et al., Shock 2004 (Reperfusion Injury...) : Administration of WY 14643 also markedly reduced the nitrotyrosine formation, poly ( adenosine diphosphate [ ADP ] -ribose ) polymerase ( PARP ) activation , up-regulation of ICAM-1 , and expression of P-selectin during reperfusion
Qin et al., Biochim Biophys Acta 2013 (Inflammation) : Moreover, PARP-1 inhibition attenuated LSS induced iNOS and ICAM-1 upregulation by inhibiting nuclear factor kappa B ( NF-?B ) nuclear translocation and activity, with a reduced NF-?B phosphorylation