Gene interactions and pathways from curated databases and text-mining

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HSPG2 — IGF2

Text-mined interactions from Literome

El-Shewy et al., Mol Endocrinol 2011 : Taken together, these data provide evidence that activation of PLC and PKCß2 by the IGF-II/M6P receptor are required for the activation of SK1
Miyagishima et al., Hokkaido Igaku Zasshi 1993 (Fibrosarcoma) : These findings suggest that IGF II stimulates PLC through binding to the IGF II/Man-6-P receptor
Yu et al., Biochim Biophys Acta 1996 (Insulin Resistance) : Phospholipase C (PLC) , which cleaves phospholipids at the cell surface, markedly enhanced cell surface 125I-IGF-II binding in a concentration dependent manner