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HSD17B1 — IGF2

Text-mined interactions from Literome

Wong et al., Pathology 2001 (Breast Neoplasms) : The aim of this study was to assess the effects of transforming growth factor-beta1 ( TGFbeta1 ), insulin-like growth factor-I (IGF-I) and insulin-like growth factor-II (IGF-II) on cell growth, E1STS and E2DH activities in the MCF-7 and MDA-MB-231 human breast cancer cell lines ... In the MCF-7 cells, TGFbeta1 and IGF-I, IGF-I and IGF-II, and TGFbeta1, IGF-I and IGF-II acted synergistically to stimulate the reductive E2DH activity, while only TGFbeta1, IGF-I and IGF-II synergistically stimulated the oxidative E2DH activity
Singh et al., J Endocrinol 1991 (Breast Neoplasms) : Both IGF-I ( 80 ng/ml ) and IGF-II ( 80 ng/ml ) significantly stimulated E2DH reductive activity ( up to 138 % ) in MCF-7 cells but had no effect on oxidative activity