Yang et al., Di Yi Jun Yi Da Xue Xue Bao 2003
(Adenocarcinoma...) :
The inhibition of eIF-4E strongly reduces the stability of heparanase mRNA in colon adenocarcinoma cell line LS-174T and results in an apparent reduction in the expression of heparanase protein
Yang et al., World J Gastroenterol 2003
(Adenocarcinoma...) :
eIF-4E is involved in the regulation of heparanase production in colon adenocarcinoma cell line LS-174T, and its critical function makes it a particularly interesting target for heparanase regulation
Yang et al., Chin J Cancer 2003
(Adenocarcinoma...) :
[ Role of eukaryotic initiation factor-4E (eIF-4E) in regulation of expression of NF-kappaB and its subsequent influence on transcription and activity of heparanase in human colon adenocarcinoma cell line ]
Yang et al., Zhonghua Zhong Liu Za Zhi 2003
(Adenocarcinoma...) :
To determine whether the eukaryotic initiation factor-4E (eIF-4E) is involved in the cap dependent translational regulation of heparanase and study the correlation between heparanase expression and metastatic potential of LS-174T cells ... eIF-4E , probably being involved in translational regulation of heparanase in colon adenocarcinoma cell line LS-174T, can be a particularly interesting target for heparanase regulation, based on of its critical function