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HNF1A — WNT11

Text-mined interactions from Literome

Galceran et al., Genes Dev 1999 (Limb Deformities, Congenital) : Together, these data provide evidence for a redundant role of LEF-1 and TCF-1 in Wnt signaling during mouse development
Agarwal et al., Development 2003 (Limb Deformities, Congenital) : Lef1/Tcf1 dependent Wnt signaling is not essential for initiation of Tbx5 or Fgf10 transcription, but is required in concert with Tbx5 for maintenance of normal levels of Fgf10 expression
Yi et al., Nat Cell Biol 2011 : Interestingly, both Tcf3-ß-catenin and Tcf1-ß-catenin interactions contributed to Wnt stimulation of self-renewal and gene expression, and the combination of Tcf3 and Tcf1 recruited Wnt stabilized ß-catenin to Oct4 binding sites on ESC chromatin
Tiemessen et al., PLoS Biol 2012 (Genetic Predisposition to Disease...) : Loss of Tcf1 as repressor of Lef1 leads to high Wnt activity and is the initiating event in lymphoma development, which is exacerbated by activating Notch1 mutations
Nault et al., International journal of hepatology 2013 : Three major molecular pathways have been identified altered in specific HCA subgroups that are defined by either ( 1 ) inactivation of hepatocyte nuclear factor 1A (HNF1A) transcription factor, ( 2 ) activation of the WNT/ß-catenin by CTNNB1 mutations, or ( 3 ) activation of the IL6/STAT3 pathway by somatic mutation of IL6ST, GNAS, or STAT3