Gene interactions and pathways from curated databases and text-mining

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HGS — IGF1

Text-mined interactions from Literome

Sakai et al., Endocrinology 2003 (Carcinoma, Hepatocellular...) : These studies were undertaken to analyze the role of IGF-I, insulin, and insulin/IGF-I hybrid receptors (HRs) in mediating IGF-I and insulin signaling in cells that had been made insulin-resistant by treatment with glucosamine ... Exposure to glucosamine also resulted in a reduction in the ability of IGF-I or insulin to stimulate phosphorylation of insulin IGF-I/HRs
Belfiore et al., J Mammary Gland Biol Neoplasia 2008 (Breast Neoplasms) : Moreover, overexpression of both IGF-IR and IR-A in breast cancer cells, leads to overexpression of hybrid IR/IGF-IR receptors (HRs) as well