Gene interactions and pathways from curated databases and text-mining

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HGF — IL5

Text-mined interactions from Literome

Shindoh et al., Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 1999 (Pulmonary Eosinophilia) : It was also shown that IL-5 induced the production of HGF by peripheral eosinophiles in vitro
Matsumoto et al., Biochem Biophys Res Commun 1992 : Up-regulation of hepatocyte growth factor gene expression by interleukin-1 in human skin fibroblasts
Takami et al., Biochem Biophys Res Commun 2004 : HGF production is induced by the activation of protein kinase A and protein kinase C-mediated pathways, interleukin (IL)-1 , tumor necrosis factor (TNF)-alpha, and epidermal growth factor (EGF) in mesenchymal cells
Knowles et al., Clin Cancer Res 2009 (Carcinoma, Squamous Cell...) : c-Met TKIs blocked HGF induced signaling, interleukin-8 release, and wound healing
Schmeding et al., Transplantation 2010 (Fatty Liver) : Analysis of liver enzymes, histology ( hematoxylin-eosin and periodic acid Schiff stain ), immunostaining ( terminal deoxynucleotide transferase- mediated dUTP nick-end labeling, hypoxyprobe, and tumor necrosis factor-alpha ), and reverse transcriptase-polymerase chain reaction of cytokine messenger RNA ( interleukin-1 , interleukin-6, hypoxia induced factor-1 alpha, vascular endothelial growth factor, and hepatocyte growth factor ) were performed at defined time points ( 2, 4.5, 24, 48 hr, and 7 days postoperatively )
Chen et al., Stem Cells Dev 2011 (Acute Kidney Injury...) : Real-time polymerase chain reaction result showed that HGF-hucMSCs also inhibited caspase-3 and interleukin-1ß mRNA expression in injured renal tissues
Wang et al., Hum Gene Ther 2013 (Disease Models, Animal...) : MSCs-HGF could reduce secretion and expression of proinflammatory cytokines, including tumor necrosis factor-a, interferon-?, interleukin (IL)-6, and intercellular adhesion molecule-1, and increase the expression of antiinflammatory cytokine IL-10
Bazin et al., J Immunol 1987 (Ascites...) : The HGF activity was not mediated by interleukin 1 because the two activities could be completely separated by gel filtration
Sugiyama et al., Infect Immun 1996 : Lipoteichoic acid and interleukin 1 stimulate synergistically production of hepatocyte growth factor ( scatter factor ) in human gingival fibroblasts in culture
Gohda et al., J Cell Physiol 1998 (Leukemia) : Granulocyte colony stimulating factor ( G-CSF ), granulocyte/macrophage colony stimulating factor ( GM-CSF ), interleukin (IL)-5 and IL-6 had no effect on HGF/SF production in the 2 leukemia cell lines
Bamba et al., Biochem Biophys Res Commun 1998 (Peptic Ulcer...) : Among various potential stimulants tested, interleukin-1 beta (IL-1 beta) dramatically increased PGE2 production and significantly stimulated HGF production
Miyazaki et al., Biochem Biophys Res Commun 1998 : Increased hepatocyte growth factor production by aging human fibroblasts mainly due to autocrine stimulation by interleukin-1 ... The increased production of HGF by aging fibroblasts from human embryonic lung tissue is mainly due to autocrine stimulation by interleukin-1