Gene interactions and pathways from curated databases and text-mining

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HDAC6 — IL5

Text-mined interactions from Literome

Jee et al., J Biol Chem 2005 (Inflammation) : Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment
Rehni et al., Naunyn Schmiedebergs Arch Pharmacol 2012 (Opioid-Related Disorders...) : The present study has been designed to investigate the effect of selective inhibitors of histone deacetylase and/or N-acetyl-Asp-Glu-Val-Asp-al ( Ac-DEVD-CHO ), a selective interleukin-1ß converting enzyme inhibitor , on the development of naloxone induced opioid withdrawal syndrome both in vitro and in vivo and the effect of histone deacetylase inhibition on histone H3 acetylation in brain
Payeli et al., Arthritis Rheum 2012 (Arthritis, Rheumatoid...) : Finally, HD6 inhibited production of the proinflammatory disease associated cytokine interleukin-17 by PBMCs from patients with AS