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CXCR4 — HDAC2
Text-mined interactions from Literome
Mori et al., Cancer Res 2005
(Melanoma...) :
In summary, a
histone deacetylase inhibitor and a demethylating agent
up-regulated CCR7 and
CXCR4 expression on melanoma cells
Gul et al., Stem Cells Dev 2009
:
We hypothesized that in HSPCs the
CXCR4 receptor is
regulated through chromatin remodeling by
histone deacetylase inhibitors ( HDIs ) such as valproic acid ( VPA )
Gul et al., Leuk Res 2010
(Leukemia...) :
We recently reported that the
histone deacetylase inhibitor, valproic acid ( VPA ),
increases CXCR4 receptor expression and function in cord blood hematopoietic stem/progenitor cells ( HSPC ) and the immature, highly CD34 positive AML cell lines KG-1a and KG-1
Iordache et al., International journal of molecular sciences 2012
:
RT-PCR assay showed that
HDAC inhibitors
down-regulated the expression of endothelial genes such as VE-cadherin, CD133,
CXCR4 and Tie-2 ... RT-PCR assay showed that
HDAC inhibitors
down-regulated the expression of endothelial genes such as VE-cadherin, CD133,
CXCR4 and Tie-2