Gene interactions and pathways from curated databases and text-mining

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HDAC1 — MAPK3

Text-mined interactions from Literome

Wu et al., J Clin Invest 2002 (Myotonia Congenita) : These findings suggest that the combined effects of class II HDAC deficiency and p38 MAPK activation lead to potent upregulation of MEF2 transcriptional activity, which contributes to the long-term changes in gene expression and fiber-type transformation observed in myotonic skeletal muscles
Jansen et al., Proc Natl Acad Sci U S A 2004 : Short-chain fatty acids enhance nuclear receptor activity through mitogen activated protein kinase activation and histone deacetylase inhibition
Bode et al., Immunology 2007 : In contrast, HDAC inhibitors had no effects on upstream nuclear factor-kappaB and mitogen activated protein kinase activation