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ARF6 — HDAC1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 400 proteins (association, cross-linking study) Humphries et al., Science signaling 2009

Text-mined interactions from Literome

Matheu et al., J Biol Chem 2005 : Regulation of the INK4a/ARF locus by histone deacetylase inhibitors
Paliwal et al., Mol Cell Biol 2006 (Colonic Neoplasms) : Interaction with ARF resulted in proteasome dependent CtBP degradation ... Both ARF induced CtBP degradation and CtBP small interfering RNA led to p53 independent apoptosis in colon cancer cells ... ARF induction of apoptosis was dependent on its ability to interact with CtBP , and reversal of ARF induced CtBP depletion by CtBP overexpression abrogated ARF induced apoptosis
Zeng et al., Cancer Res 2011 : We show that p53 is required for both HDAC and PcG to repress Arf expression