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GSK3B — MAPK3
Text-mined interactions from Literome
Mai et al., J Neurochem 2002
(Neuroblastoma) :
Overexpression of
GSK3beta did not
affect BDNF induced phosphorylation of Akt,
ERK1/2 , or FKHRL1, but abolished CREB phosphorylation induced by BDNF
Kim et al., J Biol Chem 2003
:
Glycogen synthase kinase 3 beta is a natural
activator of
mitogen activated protein kinase/extracellular signal regulated kinase kinase kinase 1 ( MEKK1 )
Wong et al., Life Sci 2005
(Enterovirus Infections) :
The activity of
GSK3beta , a downstream target of these pathways, was negatively
regulated by the activation of both
MAPK/ERK and PI3K/Akt
D'Alimonte et al., Neurosci Lett 2007
:
Our research shows that rat astrocyte exposure to 100 nM staurosporine for 3h caused apoptotic death accompanied by caspase-3, p38 mitogen ed protein kinase (
MAPK ) and
glycogen synthase kinase-3beta ( GSK3beta )
activation
Bikkavilli et al., J Cell Sci 2008
:
We also demonstrate that chemical inhibition of p38
MAPK restores Wnt3a attenuated
GSK3beta kinase activity