Gene interactions and pathways from curated databases and text-mining

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GSK3B — MAPK3

Text-mined interactions from Literome

Mai et al., J Neurochem 2002 (Neuroblastoma) : Overexpression of GSK3beta did not affect BDNF induced phosphorylation of Akt, ERK1/2 , or FKHRL1, but abolished CREB phosphorylation induced by BDNF
Kim et al., J Biol Chem 2003 : Glycogen synthase kinase 3 beta is a natural activator of mitogen activated protein kinase/extracellular signal regulated kinase kinase kinase 1 ( MEKK1 )
Wong et al., Life Sci 2005 (Enterovirus Infections) : The activity of GSK3beta , a downstream target of these pathways, was negatively regulated by the activation of both MAPK/ERK and PI3K/Akt
D'Alimonte et al., Neurosci Lett 2007 : Our research shows that rat astrocyte exposure to 100 nM staurosporine for 3h caused apoptotic death accompanied by caspase-3, p38 mitogen ed protein kinase ( MAPK ) and glycogen synthase kinase-3beta ( GSK3beta ) activation
Bikkavilli et al., J Cell Sci 2008 : We also demonstrate that chemical inhibition of p38 MAPK restores Wnt3a attenuated GSK3beta kinase activity