Gene interactions and pathways from curated databases and text-mining

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GRM1 — MAPK3

Text-mined interactions from Literome

Sheffler et al., Neuropharmacology 2008 : In baby hamster kidney ( BHK ) cells, mGluR1 activates calcium mobilization, cAMP production, and extracellular signal regulated kinase 1/2 ( ERK1/2 ) phosphorylation ; signaling cascades which are distinct and differentially regulated
Wangari-Talbot et al., Mol Cancer Res 2012 (MAP Kinase Signaling System...) : We showed that suppression of GRM1 expression in several human melanoma cell lines resulted in a reduction in the number of viable cells and a decrease in stimulated mitogen activated protein kinase ( MAPK ) and PI3K/AKT and suppressed tumor progression in vivo