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AKT1 — GRIP1

Text-mined interactions from Literome

Duong et al., Cancer Res 2006 (Breast Neoplasms) : Mammalian two-hybrid assays revealed that AKT enhanced both SRC1 and GRIP1 recruitment to the ER beta-AF2 domain, and reporter gene analyses revealed that AKT and GRIP1 cooperatively potentiated ER beta mediated transcription to a level much greater than either factor alone ... Investigations into AKT regulation of GRIP with mammalian one-hybrid assays showed that AKT potentiated the activation domains of GRIP1 itself, and in vitro kinase assays revealed that AKT directly phosphorylated GRIP1
Bratton et al., Int J Oncol 2010 (Breast Neoplasms) : In addition, AKT also caused an upregulation of GRIP1 protein levels