Gene interactions and pathways from curated databases and text-mining

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GPER1 — PRKAR2A

Text-mined interactions from Literome

Hsieh et al., Am J Pathol 2007 (Hemorrhage...) : We found that suppression of GPR30 but not ER-alpha prevented E2-BSA- or E2-induced PKA activation and Bcl-2 expression
Ding et al., Am J Physiol Cell Physiol 2009 : Thus the effect of estradiol on vascular smooth muscle cell apoptosis is likely dependent on the balance between ER-mediated PKA activation and GPR30 mediated PKA inhibition and PI3 kinase activation