Gene interactions and pathways from curated databases and text-mining

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CXCR4 — GNGT1

Pathways - manually collected, often from reviews:

  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: G-protein receptor/G-gamma/G-beta/G-alpha-S/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNGT1-GNB1-GNAS) → G-alpha-s/GTP complex (GNAS) (modification, collaborate)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: G-protein receptor/G-gamma/G-beta/G-alpha-S/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNGT1-GNB1-GNAS) → Ligand (CCL4/EDN1//AGT/CCL11/CXCL12/F2) (modification, collaborate)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: G-protein receptor/G-gamma/G-beta/G-alpha-S/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNGT1-GNB1-GNAS) → Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) (modification, collaborate)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: G-alpha-s/GTP complex (GNAS) → Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) (modification, collaborate)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: Ligand (CCL4/EDN1//AGT/CCL11/CXCL12/F2) → Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) (modification, collaborate)
  • BioCarta chrebp regulation by carbohydrates and camp: Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) → GPCR/g-alpha-s/g-beta/g-gamma/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNAS-GNGT1-GNB1) (modification, collaborate)
  • BioCarta chrebp regulation by carbohydrates and camp: Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) → GTP/G-alpha-S complex (GNAS) (modification, collaborate)
  • BioCarta chrebp regulation by carbohydrates and camp: Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) → Ligand (CCL4/EDN1//AGT/CCL11/CXCL12/F2) (modification, collaborate)
  • BioCarta chrebp regulation by carbohydrates and camp: GPCR/g-alpha-s/g-beta/g-gamma/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNAS-GNGT1-GNB1) → GTP/G-alpha-S complex (GNAS) (modification, collaborate)
  • BioCarta chrebp regulation by carbohydrates and camp: GPCR/g-alpha-s/g-beta/g-gamma/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNAS-GNGT1-GNB1) → Ligand (CCL4/EDN1//AGT/CCL11/CXCL12/F2) (modification, collaborate)
  • BioCarta cxcr4 signaling pathway: G-alpha-i/G-beta/G-gamma complex (GNAI1-GNGT1-GNB1) → SDF-1/CXCR4/g-alpha-q complex (CXCL12-CXCR4-GNAQ) (modification, collaborate)
  • BioCarta activation of camp-dependent protein kinase pka: G-protein receptor/G-gamma/G-beta/G-alpha-S/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNGT1-GNB1-GNAS) → G-alpha-s/GTP complex (GNAS) (modification, collaborate)
  • BioCarta activation of camp-dependent protein kinase pka: G-protein receptor/G-gamma/G-beta/G-alpha-S/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNGT1-GNB1-GNAS) → G-protein receptor/G-gamma/G-beta/Ligand complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNGT1-GNB1-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3) (modification, collaborate)
  • BioCarta activation of camp-dependent protein kinase pka: G-protein receptor/G-gamma/G-beta/G-alpha-S/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNGT1-GNB1-GNAS) → Ligand (CCL4/EDN1//AGT/CCL11/CXCL12/F2) (modification, collaborate)
  • BioCarta activation of camp-dependent protein kinase pka: G-alpha-s/GTP complex (GNAS) → G-protein receptor/G-gamma/G-beta/Ligand complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNGT1-GNB1-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3) (modification, collaborate)
  • BioCarta activation of camp-dependent protein kinase pka: G-protein receptor/G-gamma/G-beta/Ligand complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNGT1-GNB1-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3) → Ligand (CCL4/EDN1//AGT/CCL11/CXCL12/F2) (modification, collaborate)
  • BioCarta roles of ß arrestin dependent recruitment of src kinases in gpcr signaling: Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) → GPCR/g-alpha-s/g-beta/g-gamma/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNAS-GNGT1-GNB1) (modification, collaborate)
  • BioCarta roles of ß arrestin dependent recruitment of src kinases in gpcr signaling: Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) → G-alpha-s/GTP complex (GNAS) (modification, collaborate)
  • BioCarta roles of ß arrestin dependent recruitment of src kinases in gpcr signaling: Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) → Ligand (CCL4/EDN1//AGT/CCL11/CXCL12/F2) (modification, collaborate)
  • BioCarta roles of ß arrestin dependent recruitment of src kinases in gpcr signaling: GPCR/g-alpha-s/g-beta/g-gamma/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNAS-GNGT1-GNB1) → G-alpha-s/GTP complex (GNAS) (modification, collaborate)
  • BioCarta roles of ß arrestin dependent recruitment of src kinases in gpcr signaling: GPCR/g-alpha-s/g-beta/g-gamma/GDP complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-GNAS-GNGT1-GNB1) → Ligand (CCL4/EDN1//AGT/CCL11/CXCL12/F2) (modification, collaborate)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: atp:[beta-adrenergic-receptor] phosphotransferase (ADRBK1) → Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) (modification, activates)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: atp:[beta-adrenergic-receptor] phosphotransferase (ADRBK1) → Ligand/GPCR(+)/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) (modification, activates)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: Ligand/GPCR/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) → Ligand/GPCR(+)/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) (modification, collaborate)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: g-gamma/g-beta complex (GNGT1-GNB1) → Ligand/GPCR(+)/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) (modification, collaborate)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: Ligand/GPCR(+)/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) → Ligand/GPCR(+)/Arrestin complex (CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-ARRB1) (modification, collaborate)
  • BioCarta role of ß-arrestins in the activation and targeting of map kinases: Ligand/GPCR(+)/g-beta/g-gamma complex (HTR2C_ADRA1B_AGTR2_CHRM1_CCR5_PTGER1_P2RY2_CCR3_CXCR4_FPR1_ADRB2-CCL4_EDN1__AGT_CCL11_CXCL12_F2_compound:CAS66575-29-9_compound:CAS745-65-3-GNGT1-GNB1) → Arrestin (ARRB1) (modification, collaborate)