Gene interactions and pathways from curated databases and text-mining

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GNAS — PRKAR2A

Pathways - manually collected, often from reviews:

  • BioCarta attenuation of gpcr signaling: NT/GPCR/g-alpha/g-beta/g-gamma complex (GNB1-GNAS-GNGT1) → PKA complex (PRKACB-PRKACG-PRKAR1A-PRKAR1B-PRKAR2A-PRKAR2B) (modification, collaborate)
  • BioCarta attenuation of gpcr signaling: PKA complex (PRKACB-PRKACG-PRKAR1A-PRKAR1B-PRKAR2A-PRKAR2B) → g-alpha/g-beta/g-gamma complex (GNAS-GNB1-GNGT1) (modification, activates)