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GJA1 — MAPK14

Text-mined interactions from Literome

Hossain et al., J Cell Physiol 1999 : Since many of these agents activate additional protein kinases, our present study examined whether activation of MAPK was sufficient for Cx43 phosphorylation and GJC blockade
Carystinos et al., Mol Pharmacol 2003 : This study provides evidence that the transcriptional up-regulation of Cx43 by Ras-Raf-MAPK is mediated via the interaction of a novel Cx43 promoter element with a protein complex that contains both HSP90 and c-Myc
Kalma et al., Endocrinology 2004 : We show herein that LH inhibits Cx43 expression by reducing its rate of translation and that this effect is mediated by both PKA and MAPK
Chung et al., Toxicological sciences : an official journal of the Society of Toxicology 2006 : Previously, we reported that 2,2'-dichlorobiphenyl ( 2,2'-DCB ) -induced decreases of amplitude and synchronization of uterine contractions are dependent on MAPK induced phosphorylation of Connexin43 (Cx43) and inhibition of myometrial gap junctions ... Furthermore, cotreatment with SOD or Def was unable to prevent 2,2'-DCB induced phosphorylation of Cx43 , activation of MAPK , and inhibition of myometrial gap junctions
Wang et al., BMC cell biology 2011 : AGE-BSA down-regulated Cx43 expression in HAEC, mainly through reduced Cx43 transcription, and the process involved activation of ERK and p38 MAPK
Johnstone et al., Circ Res 2012 (Atherosclerosis) : Coimmunoprecipitation studies in primary VSMC isolated from Cx43 wild-type ( Cx43 ( +/+ ) ) and Cx43 null ( Cx43 ( -/- ) ) mice and analytic size exclusion studies of purified proteins identify that interactions between cyclin E and Cx43 requires Cx43 MAPK phosphorylation
Negoro et al., Scientific reports 2013 (Disease Models, Animal...) : SB203580 ( p38 MAPK inhibitor ) prevented IL-1ß induced Cx43 upregulation
Hossain et al., J Cell Physiol 1998 : Platelet derived growth factor induced disruption of gap junctional communication and phosphorylation of connexin43 involves protein kinase C and mitogen activated protein kinase