Gene interactions and pathways from curated databases and text-mining

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GIPC1 — IGF1

Text-mined interactions from Literome

Muders et al., Cancer Res 2006 (Adenocarcinoma...) : Here, we described GIPC expression in different human pancreatic adenocarcinoma ( PCA ) cell lines and we examined the role of GIPC in the regulation of IGF-IR protein levels in PCA ... Interestingly, inhibition of GIPC expression by RNA interference led to reduced IGF-IR protein levels and a subsequent decrease in proliferation of PCA cells
Paek et al., Mol Cells 2011 (Colonic Neoplasms) : Taken together, these data suggest that GIPC is involved in IGF-1 signaling leading to ZNF143 expression through the regulation of ROS production, which may play a role for colon cancer tumorigenesis