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GHSR — NOS1

Text-mined interactions from Literome

Iantorno et al., Am J Physiol Endocrinol Metab 2007 : Production of NO in response to ghrelin ( 100 nM, 10 min ) in human aortic endothelial cells was blocked by pretreatment of cells with NG-nitro-L-arginine methyl ester ( nitric oxide synthase inhibitor ), wortmannin [ phosphatidylinositol (PI) 3-kinase inhibitor ], or ( D-Lys3 ) -GHRP-6 ( selective antagonist of ghrelin receptor GHSR-1a ), as well as by knockdown of GHSR-1a using small interfering ( si ) RNA ( but not by mitogen/extracellular signal regulated kinase inhibitor PD-98059 )
Pazos et al., Vitam Horm 2008 : At molecular level, GHSR1a regulates the activation of the downstream mitogen activated protein kinase, Akt, nitric oxide synthase , and AMPK cascades in different cellular systems