Gene interactions and pathways from curated databases and text-mining

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GCG — NPY

Text-mined interactions from Literome

Ponery et al., Peptides 2000 (Diabetes Mellitus, Experimental) : In addition to this, the effect of NPY and SP on glucagon secretion was also examined in the pancreases of normal and diabetic rats ... In contrast to this, NPY inhibited glucagon secretion from the pancreas of diabetic rat ... In conclusion, NPY and SP stimulated glucagon secretion from the pancreas of normal rat ... In contrast, NPY and SP inhibited glucagon secretion from diabetic rat pancreas
Opara et al., Regul Pept 1991 : Available data on the effect of neuropeptide Y (NPY) on insulin release are conflicting and little data exist regarding the effect of NPY on glucagon secretion
Geraedts et al., J Neurosci 2013 : Appetitive stimuli ( sweet : glucose, sucralose ; umami : monosodium glutamate ; polysaccharide : Polycose ) elicited GLP-1 and NPY secretion and inhibited basal glucagon secretion
Dunning et al., Regul Pept 1987 : Immunofluorescent staining for neuropeptide Y (NPY) in canine pancreatic tissue was performed together with an evaluation of the effects of synthetic NPY on the release of insulin ( IRI ), glucagon ( IRG ) and somatostatin ( SLI ) from the duodenal lobe of the canine pancreas in situ
Pettersson et al., Endocr Res 1987 : Glucagon secretion stimulated by the cholinergic agonist carbachol was modestly inhibited by NPY at 4.25 nmol/kg ( P less than 0.01 ) but not affected by CGRP ... In contrast, glucagon secretion stimulated by the beta 2-adrenoceptor agonist terbutaline was markedly inhibited by NPY already at the lower dose level ( P less than 0.01 ) and potentiated by CGRP ( P less than 0.01 )
Marks et al., J Neuroendocrinol 1996 : The purpose of this study was to compare the effects of NPY injected into the third ventricle ( ICV ) on serum insulin, glucose, glucagon , corticosterone and non esterified fatty acids
Parikh et al., J Neuroendocrinol 1997 (Insulin Resistance) : In the fed but not fasted state, 3 micrograms ICV NPY increased plasma glucagon and corticosterone levels and attenuated the decline in blood glucose during the ITT