Gene interactions and pathways from curated databases and text-mining

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GATA4 — IGF1

Text-mined interactions from Literome

LaVoie et al., Endocrinology 2004 : These data indicate that GATA-4 and C/EBPbeta are both required for FSH +/- IGF-I stimulation of the porcine steroidogenic acute regulatory protein gene promoter in homologous granulosa cell cultures
Li et al., Chin Med J (Engl) 2008 : HGF and IGF-1 can stimulate transdifferentiation of BMSCs into cardiac phenotype and enhance the expression of GATA-4
Bisping et al., J Biol Chem 2012 (Cardiomegaly) : IGF1 and PE both increased nuclear accumulation of GATA4 and phosphorylation at Ser ( 105 ) ( PE, 2.4-fold ; IGF1, 1.8-fold ; both, p < 0.05 ) and increased GATA4 DNA binding activity as indicated by ELISA and by chromatin IP of selected promoters ... Although IGF1 and PE each activated GATA4 to the same degree, GATA4 knockdown by RNA interference only blocked hypertrophy by PE but not by IGF1
Sharma et al., Reproduction 2012 : Conjugated linoleic acids attenuate FSH- and IGF1 stimulated cell proliferation ; IGF1, GATA4 , and aromatase expression ; and estradiol-17ß production in buffalo granulosa cells involving PPAR?, PTEN, and PI3K/Akt