Gene interactions and pathways from curated databases and text-mining

◀ Back to IL12A

GATA3 — IL12A

Text-mined interactions from Literome

Lantelme et al., Immunology 2001 : During T-cell commitment the presence of IL-4 in the culture was essential to maintain or enhance GATA-3 transcription, while IL-12 was not necessary for full repression of GATA-3
Filén et al., Mol Cell Proteomics 2009 : Besides T cell receptor signaling, IL-12 induced STAT4 and T-bet- and IL-4 induced STAT6 and GATA3 signaling pathways are the major players regulating the Th1 and Th2 differentiation process, respectively
Ouyang et al., Immunity 1998 : Here, we show that loss of GATA-3 expression by developing Th1 cells requires IL-12 signaling through Stat4 and does not simply result from an absence of IL-4